tag:blogger.com,1999:blog-18943510.post959880605707196378..comments2023-08-21T02:57:37.362-05:00Comments on Dr. Wes: Stem Cells Create Beating Heart MuscleDrWeshttp://www.blogger.com/profile/17438019699222125477noreply@blogger.comBlogger15125tag:blogger.com,1999:blog-18943510.post-82001565556421331742007-02-02T21:46:00.000-06:002007-02-02T21:46:00.000-06:00You needn't worry that you won't be able to afford...You needn't worry that you won't be able to afford the treatment in 6, 10, or 20 years. It simply won't exist. All the ES cell lines, including the "non-presidential" ones generated at Doug Melton's lab over at Harvard, are miserable failures at growing for many passages. Like I said before, people don't even know how to culture them long enough to do valuable research on them.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-18943510.post-64495100409883617422007-01-19T12:13:00.000-06:002007-01-19T12:13:00.000-06:00That is interesting. With the ability to create b...That is interesting. With the ability to create beating heart muscles, we'll be able to heal people that have heart disease but the thing I am not looking forward to is the price of this technology. Since this will be approved in the next 10 years, probably six, the price will only be affordable by millionaires and not for the common folk like every other medicine. I hope that this becomes Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-18943510.post-42430533171534601322007-01-18T05:46:00.000-06:002007-01-18T05:46:00.000-06:00Anonymous: You could be right, or wrong, we...Anonymous: You could be right, or wrong, we just don't know. As the recent <a href="http://www.nature.com/nbt/journal/v25/n1/abs/nbt1274.html">research report</a> which announced the amniotic fluid stem cell results notes, it's not clear yet whether the AF stem cells truly are <i>pluripotent</i> — able to grow into all the cells and tissues of the body. Since as noted Michael McNeilhttps://www.blogger.com/profile/08007336342718478839noreply@blogger.comtag:blogger.com,1999:blog-18943510.post-90715014687775521172007-01-17T22:04:00.000-06:002007-01-17T22:04:00.000-06:00Great news. Ill bet stem cells from amniotic fluid...Great news. Ill bet stem cells from amniotic fluid couldnt do that.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-18943510.post-18316134467963322132007-01-17T13:38:00.000-06:002007-01-17T13:38:00.000-06:00This is nice and all, but people are already recei...This is nice and all, but people are already receiving treatments for heart problems using adult stem cells.<br />http://www.stemcellresearch.org/facts/ASCRvESCRHeart.pdf<br /><br />This would be useful for patients whose heart is damaged enough that a complete transplant is required.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-18943510.post-80137329493802423682007-01-17T12:42:00.000-06:002007-01-17T12:42:00.000-06:00James: I said it wasn't a “breakthrou...James: I <i>said</i> it wasn't a “breakthrough” — are you denying that it's a “significant step”? How about just a step?<br /><br />I think your pessimism — except with regard to the fact that it's going to take many more years (a decade or two in my view) to attain real fluency in wielding this technology — is misplaced, particularly the Michael McNeilhttps://www.blogger.com/profile/08007336342718478839noreply@blogger.comtag:blogger.com,1999:blog-18943510.post-24061619482114459562007-01-17T06:28:00.000-06:002007-01-17T06:28:00.000-06:00McNeil -
It's not even close to a breakthrough, M...McNeil -<br /><br />It's not even close to a breakthrough, Most of the leading scientists in the field can't even culture ES cells correctly, let alone control their differentiation. Stem cell therapies are 10 years away in the same sense that fusion power is 10 years away, that is, only in the arguments of those applying for government grants.<br /><br />I don't think these scientists were Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-18943510.post-61327125132034131412007-01-17T02:56:00.000-06:002007-01-17T02:56:00.000-06:00Thanks for your help, James, that is just what I w...Thanks for your help, James, that is just what I wanted.<br /><br />And while no doubt this is not a breakthrough development (it's important I think to emphasize that stem cell research is still in the basic, not applied, research stage — meaning patient treatments aren't imminent — <a href="http://www.cirm.ca.gov/">California's Institute for Regenerative Medicine</a> just launched Michael McNeilhttps://www.blogger.com/profile/08007336342718478839noreply@blogger.comtag:blogger.com,1999:blog-18943510.post-10809760476250590972007-01-16T21:17:00.000-06:002007-01-16T21:17:00.000-06:00Scary? It's damned wonderful!Scary? It's damned wonderful!Jeff Fariahttps://www.blogger.com/profile/12311004609431680032noreply@blogger.comtag:blogger.com,1999:blog-18943510.post-45520608544942998122007-01-16T21:04:00.000-06:002007-01-16T21:04:00.000-06:00McNeil, try searching on the Circulation Research ...McNeil, try searching on the Circulation Research site with the author names. The abstract is free, here:<br /><br /><a href=http://circres.ahajournals.org/cgi/content/abstract/01.RES.0000257776.05673.ffv1?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=levenberg+gepstein&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT>Free Abstract</a><br /><br />The supplemental methods are also freely available. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-18943510.post-62355169996338029002007-01-16T20:57:00.001-06:002007-01-16T20:57:00.001-06:00Great news, Dr. Wes.
However -- could you point m...Great news, Dr. Wes.<br /><br />However -- could you point me to the article in question at Circulation Research? I can't follow the direct pointer you provide (as I don't have a subscription to login to), and then when I try to search for it (<a href="http://circres.ahajournals.org/">here</a>, whether using the doi or, say, "pluripotent") the article doesn't seem to turn up.Michael McNeilhttps://www.blogger.com/profile/08007336342718478839noreply@blogger.comtag:blogger.com,1999:blog-18943510.post-57037842139813083362007-01-16T20:57:00.000-06:002007-01-16T20:57:00.000-06:00Prestigious? Check the impact factor. Circulation ...Prestigious? Check the impact factor. Circulation Research is a third tier journal at best. If this was really novel ES cell work, it would have been in Cell, Science, or Nature, not some backwards clinical journal.<br /><br />Synchronously beating cells are a common occurence in ES cell culture; it's not clear that these cells are anything special. <br /><br />I'd suspect that this is probably Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-18943510.post-42944639000128372542007-01-16T00:48:00.000-06:002007-01-16T00:48:00.000-06:00Yes, it is amazing and scary. The Bears may actua...Yes, it is amazing and scary. The Bears may actually make it this year.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-18943510.post-91773764987907195172007-01-15T20:13:00.000-06:002007-01-15T20:13:00.000-06:00That is amazing (and kind of scary...)That is amazing (and kind of scary...)Bo...https://www.blogger.com/profile/02136803397641401011noreply@blogger.comtag:blogger.com,1999:blog-18943510.post-22859822748842139162007-01-15T12:34:00.000-06:002007-01-15T12:34:00.000-06:00very cool! See ya next week. go bears!very cool! See ya next week. go bears!Anonymousnoreply@blogger.com